Name | 5-Carboxytetramethylrhodamine |
Synonyms | 5-TAMRA CS-1311 5-CarboxytetraMethyl 5-Carboxytetramethylrhodamine 5-CARBOXYTETRAMETHYLRHODAMINE*(SINGLE ISOMER) 5-TAMRA [5-Carboxytetramethylrhodamine] *Single isomer* 9-(2,4-Dicarboxyphenyl)-3,6-bis(diMethylaMino)xanthyliuM 2-(3,6-Bis(diMethylaMino)xanthyliuM-9-yl)-5-carboxybenzoate 3-carboxy-4-[6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]benzoate |
CAS | 91809-66-4 |
InChI | InChI=1/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31) |
InChIKey | YMZMTOFQCVHHFB-UHFFFAOYSA-N |
Molecular Formula | C25H22N2O5 |
Molar Mass | 430.45 |
Water Solubility | DMSO: soluble |
Solubility | DMSO: soluble |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
MDL | MFCD01073638 |
Physical and Chemical Properties | 5-carboxytetramethylrhodamine, also known as 5-TAMRA [5-Carboxytetramethylrhodamine], is a fluorescent reagent that can be used to make carboxyfluorescein-oligonucleotide-carboxytetramethylrhodamine (FAM-DNA- TAMRA) fluorescent probes. |
Use | An important fluorescent group for the detection of TMR-labeled amino acids in capillary electrophoresis |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10 |
HS Code | 3204 90 00 |
Reference Show more | 1. [IF=10.618] Mingliang Mei et al."A general configurational strategy to quencher-free aptasensors."Biosens Bioelectron. 2021 Apr;178:113025 2. [IF=2.464] Bing Jie Jia et al."Synthesis of molecularly imprinted microspheres and development of a fluorescence method for detection of chloramphenicol in meat."Luminescence. 2021 Nov;36(7):1767-1774 |
Physical and chemical properties | 5-carboxytetramethylrhodamine, also known as 5-TAMRA [5-Carboxytetramethylrhodamine] is a fluorescent reagent that can be used to make carboxyfluorescein-oligonucleotide-carboxytetramethylrhodamine (FAM-DNA- TAMRA) fluorescent probes. |
Use | 5-carboxytetramethylrhodamine is used to prepare lamp-pumped solid Nd: The coolant of the YAG laser. As a branch of laser types, lamp-pumped solid Nd:YAG (neodymium-doped yttrium aluminum garnet) lasers have been playing an important role in industrial production, scientific research, and medical treatment. Its core mechanism is the use of inert gas lamps, metal vapor lamps and other broad-spectrum light sources As a pump source, the light emitted by it is absorbed by the solid laser material, so that the solid Nd:YAG laser material produces a particle number flip, which in turn produces a laser. |
biological activity | 5-TAMRA (5-Carboxytetramethylrhodamine) can produce bright, pH-insensitive orange-red fluorescence (excitation and emission extremum is 546/579) with good light stability. |